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Professor Sir Roy Anderson
Mathematical modelling is about to become a key tool in the fight against neglected tropical diseases. That’s the prediction of Professor Sir Roy Anderson, chair in Infectious Disease Epidemiology, and expert in theoretical epidemiology at Imperial College, London.
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Mar 25 2010

Seroprevalence of human Trypanosoma cruzi infection in different geographic zones of Chiapas, Mexico.

Posted by: BIREME Web Master Group

A serologic survey was carried out in four different geographic zones of Chiapas, Mexico. A total of 1,333 samples were collected from residents of thirteen communities located on the Coast, Central Mountain, Lacandon Forest and a zone called Mesochiapas. One hundred and fifty one seropositive individuals (11.3%) were identified. Human Trypanosoma cruzi infection was influenced [...]

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Mar 25 2010

Social and epidemiological determinants of Chagas disease: basic information for a surveillance and control policy in the Southern Cone

Posted by: BIREME Web Master Group

1. Which are the neglected or emerging aspects in the discussed issue that need information and additional knowledge for the formulation of a policy for surveillance and Chagas disease control?
Vector control – There are two recognized basic strategies for vector control and prevention of Chagas disease. The first one is the destruction of intra and [...]

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Mar 25 2010

Current situation of Chagas disease in Central America.

Posted by: BIREME Web Master Group

Chagas disease in Central America is known since 1913 when the first human case was reported in El Salvador. The other Central American countries reported their first cases between 1933 and 1967. On October 1997 was launched the Central American Initiative for Chagas Disease Control (IPCA). The objectives of this sub-regional Initiative are: (1) the [...]

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Mar 25 2010

Problems and perspectives for Chagas disease control: in search of a realistic analysis

Posted by: BIREME Web Master Group

ABSTRACT: Chagas disease was an important medical and social problem in almost all of Latin America throughout the twentieth century. It has been combated over a broad swath of this continent over recent decades, with very satisfactory results in terms of vector and transfusional transmission. Today, a surveillance stage still remains to be consolidated, in [...]

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Mar 25 2010

Epidemiology, control and surveillance of Chagas disease – 100 years after its discovery

Posted by: BIREME Web Master Group

ABSTRACT: Chagas disease originated millions of years ago as an enzootic infection of wild animals and began to be transmitted to humans as an anthropozoonosis when man invaded wild ecotopes. While evidence of human infection has been found in mummies up to 9,000 years old, endemic Chagas disease became established as a zoonosis only in [...]

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Mar 25 2010

Current epidemiological trends for Chagas disease in Latin America and future challenges in epidemiology, surveillance and health policy.

Posted by: BIREME Web Master Group

ABSTRACT: Chagas disease, named after Carlos Chagas, who first described it in 1909, exists only on the American Continent. It is caused by a parasite, Trypanosoma cruzi, which is transmitted to humans by blood-sucking triatomine bugs and via blood transfusion. Chagas disease has two successive phases: acute and chronic. The acute phase lasts six-eight weeks. [...]

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Mar 25 2010

Chagas disease, migration and community settlement patterns in Arequipa, Peru.

Posted by: BIREME Web Master Group

BACKGROUND: Chagas disease is one of the most important neglected tropical diseases in the Americas. Vectorborne transmission of Chagas disease has been historically rare in urban settings. However, in marginal communities near the city of Arequipa, Peru, urban transmission cycles have become established. We examined the history of migration and settlement patterns in these communities, [...]

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Mar 25 2010

Seroprevalencia de la enfermedad de Chagas en Ushuaia, Argentina, una zona sin triatominos

Posted by: BIREME Web Master Group

Objetivos. Determinar la seroprevalencia de la infección por Trypanosoma cruzi en Ushuaia, la ciudad más austral del mundo. Métodos. Se analizaron muestras de suero de 2 991 personas, obtenidas entre enero de 1995 y diciembre de 1996. Las muestras fueron procesadas por hemaglutinación indirecta (HAI) e inmunoensayo enzimático (ELISA) o inmunofluorescencia indirecta (IFI). Resultados. La [...]

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